No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
137 |
4. Check minimum number of eventsNone |
137 |
5. Include endpointsNone |
137 |
6. Filter based on genotype QC (FinnGen only) |
134 |
Control definitions (FinnGen only)
Control exclude
E4_GLUCOPANCREAS
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
E15-E16
Name in latin
Coma hypoglychaemicum non diabeticum
Similar endpoints
↥List of similar endpoints to
Nondiabetic hypoglycaemic coma
based on the number of shared cases.
Similar with more cases:
- Other disorders of glucose regulation and pancreatic internal secretion
- Endocrine, nutritional and metabolic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1177 | 513 | 627 |
| Only index persons | 618 | 283 | 335 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.01 | 0.02 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 46.88 | 50.02 | 44.06 |
| Only index persons | 34.95 | 33.91 | 35.83 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 134 | 62 | 72 |
| Unadjusted period prevalence (%) | 0.03 | 0.02 | 0.04 |
| Median age at first event (years) | 24.56 | 25.48 | 23.77 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint E4_HYPOCOMA and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_HYPOCOMA | 4.588 [1.64, 12.87] | 0.004 |
| Birth year | 0.987 [0.98, 1.0] | 0.01 |
During the follow-up period (1.1.1998 — 31.12.2019), 67 out of 143 males with E4_HYPOCOMA died.
Mortality risk
Mortality risk for people of age
years, who have E4_HYPOCOMA.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.841% |
| 5 | No data | 5.63% |
| 10 | No data | 13.552% |
| 15 | No data | 23.531% |
| 20 | No data | 36.266% |
Relationships between endpoints
↥Index endpoint: E4_HYPOCOMA – Nondiabetic hypoglycaemic coma
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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