No definition available.
Other disorders of electrolyte and fluid balance, not elsewhere classified
EFO MESH Endpoint Browser PheWeb
E4_FLUIDELECTRONAS
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
279 |
4. Check minimum number of eventsNone |
279 |
5. Include endpointsNone |
279 |
6. Filter based on genotype QC (FinnGen only) |
271 |
Control definitions (FinnGen only)
Control exclude
E4_METABOLIA
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
E87
Name in latin
Aliae perturbationes aequilibrii electrolytici et humoralis
Similar endpoints
↥List of similar endpoints to
Other disorders of electrolyte and fluid balance, not elsewhere classified
based on the number of shared cases.
Similar with more cases:
- Other disorders of fluid, electrolyte and acid-base balance
- Metabolic disorders
- Endocrine, nutritional and metabolic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4640 | 3017 | 1556 |
| Only index persons | 2688 | 1786 | 902 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.07 | 0.09 | 0.04 |
| Only index persons | 0.06 | 0.07 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 67.70 | 70.72 | 61.89 |
| Only index persons | 65.00 | 66.77 | 61.50 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 271 | 157 | 114 |
| Unadjusted period prevalence (%) | 0.06 | 0.06 | 0.06 |
| Median age at first event (years) | 60.44 | 57.42 | 64.59 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint E4_FLUIDELECTRONAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_FLUIDELECTRONAS | 2.068 [1.65, 2.59] | < 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.524 |
During the follow-up period (1.1.1998 — 31.12.2019), 438 out of 950 females with E4_FLUIDELECTRONAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_FLUIDELECTRONAS | 5.006 [2.97, 8.43] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 272 out of 534 males with E4_FLUIDELECTRONAS died.
Mortality risk
Mortality risk for people of age
years, who have E4_FLUIDELECTRONAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.155% | 0.87% |
| 5 | 1.318% | 5.3% |
| 10 | 3.19% | 13.38% |
| 15 | 6.384% | 24.389% |
| 20 | 10.98% | 38.141% |
Relationships between endpoints
↥Index endpoint: E4_FLUIDELECTRONAS – Other disorders of electrolyte and fluid balance, not elsewhere classified
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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