No definition available.
Drug-induced headache, not elsewhere classified
DRUGADVERS_HEADA_NOT_ELSEW_CLASSIFIED
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
183 |
4. Check minimum number of eventsNone |
183 |
5. Include endpointsNone |
183 |
6. Filter based on genotype QC (FinnGen only) |
173 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF5
Similar endpoints
↥List of similar endpoints to
Drug-induced headache, not elsewhere classified
based on the number of shared cases.
Similar with more cases:
- Other headache syndromes
- Episodal and paroxysmal disorders
- Neurological diseases
- Neurological diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1129 | 777 | 342 |
| Only index persons | 1067 | 749 | 318 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.01 |
| Only index persons | 0.02 | 0.03 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 46.97 | 46.58 | 48.11 |
| Only index persons | 46.83 | 46.39 | 47.85 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 173 | 137 | 36 |
| Unadjusted period prevalence (%) | 0.05 | 0.05 | 0.02 |
| Median age at first event (years) | 48.38 | 46.97 | 53.77 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint DRUGADVERS_HEADA_NOT_ELSEW_CLASSIFIED and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| DRUGADVERS_HEADA_NOT_ELSEW_CLASSIFIED | 1.32 [1.0, 1.74] | 0.046 |
| Birth year | 0.995 [0.99, 1.0] | 0.258 |
During the follow-up period (1.1.1998 — 31.12.2019), 76 out of 665 females with DRUGADVERS_HEADA_NOT_ELSEW_CLASSIFIED died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| DRUGADVERS_HEADA_NOT_ELSEW_CLASSIFIED | 1.614 [1.08, 2.4] | 0.019 |
| Birth year | 0.989 [0.98, 1.0] | 0.076 |
During the follow-up period (1.1.1998 — 31.12.2019), 56 out of 305 males with DRUGADVERS_HEADA_NOT_ELSEW_CLASSIFIED died.
Mortality risk
Mortality risk for people of age
years, who have DRUGADVERS_HEADA_NOT_ELSEW_CLASSIFIED.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.147% | 0.348% |
| 5 | 0.718% | 1.909% |
| 10 | 1.867% | 4.967% |
| 15 | 3.603% | 9.259% |
| 20 | 6.513% | 15.684% |
Relationships between endpoints
↥Index endpoint: DRUGADVERS_HEADA_NOT_ELSEW_CLASSIFIED – Drug-induced headache, not elsewhere classified
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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