This is a non-core endpoint: only basic statistics are computed.
Functional disorders of polymorphonuclear neutrophils
D3_FUNCPOLYMORPHONUCNEUTRO
obsolete_chronic granulomatous disease: ['A recessive X-linked defect of leukocyte function in which phagocytic cells ingest but fail to digest bacteria, resulting in recurring bacterial infections with granuloma formation.']
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
24 |
4. Check minimum number of eventsNone |
24 |
5. Include endpointsNone |
24 |
6. Filter based on genotype QC (FinnGen only) |
23 |
Control definitions (FinnGen only)
Control exclude
D3_BLOODOTHER
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D70-D77
Name in latin
Dysfunctiones granulocytorum neutrophilorum segmentonuclearium
Similar endpoints
↥List of similar endpoints to
Functional disorders of polymorphonuclear neutrophils
based on the number of shared cases.
Similar with more cases:
- Other diseases of blood and blood-forming organs
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 189 | 97 | 90 |
| Only index persons | 142 | 76 | 66 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.00 | 0.00 | 0.00 |
| Only index persons | 0.00 | 0.00 | 0.00 |
| Median age at first event (years) | |||
| Whole population | 43.39 | 50.56 | 34.71 |
| Only index persons | 40.96 | 48.51 | 32.26 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 23 | 15 | 8 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.00 |
| Median age at first event (years) | 42.22 | 47.87 | 31.63 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
Mortality – FinRegistry
↥Association
Association between endpoint D3_FUNCPOLYMORPHONUCNEUTRO and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have D3_FUNCPOLYMORPHONUCNEUTRO.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: D3_FUNCPOLYMORPHONUCNEUTRO – Functional disorders of polymorphonuclear neutrophils
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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