This is a non-core endpoint: only basic statistics are computed.
Congenital dyserythropoietic anaemia
D3_CONGENDYSERYTHANAEMIA
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
23 |
4. Check minimum number of eventsNone |
23 |
5. Include endpointsNone |
23 |
6. Filter based on genotype QC (FinnGen only) |
21 |
Control definitions (FinnGen only)
Control exclude
D3_APLASTICANDOTHANAEMIA
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D64
Name in latin
Anaemia dyserythropoetica congenita
Similar endpoints
↥List of similar endpoints to
Congenital dyserythropoietic anaemia
based on the number of shared cases.
Similar with more cases:
- Other anaemias
- Aplastic and other anaemias
- Anaemias
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Any operation in hilmo
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 242 | 127 | 112 |
| Only index persons | 165 | 97 | 68 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.00 | 0.00 | 0.00 |
| Only index persons | 0.00 | 0.00 | 0.00 |
| Median age at first event (years) | |||
| Whole population | 70.67 | 72.38 | 68.67 |
| Only index persons | 65.83 | 66.47 | 64.92 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 21 | 8 | 13 |
| Unadjusted period prevalence (%) | 0.01 | 0.00 | 0.01 |
| Median age at first event (years) | 63.53 | 56.55 | 67.83 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
Mortality – FinRegistry
↥Association
Association between endpoint D3_CONGENDYSERYTHANAEMIA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_CONGENDYSERYTHANAEMIA | 2.533 [1.71, 3.76] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.187 |
During the follow-up period (1.1.1998 — 31.12.2019), 68 out of 123 females with D3_CONGENDYSERYTHANAEMIA died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have D3_CONGENDYSERYTHANAEMIA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.3% | No data |
| 5 | 1.5% | No data |
| 10 | 3.515% | No data |
| 15 | 6.704% | No data |
| 20 | 11.991% | No data |
Relationships between endpoints
↥Index endpoint: D3_CONGENDYSERYTHANAEMIA – Congenital dyserythropoietic anaemia
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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