No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
54 |
4. Check minimum number of eventsNone |
54 |
5. Include endpointsNone |
54 |
6. Filter based on genotype QC (FinnGen only) |
52 |
Control definitions (FinnGen only)
Control exclude
IBD_CMV
Extra metadata
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Cytomegaloviral pneumonitis
based on the number of shared cases.
Similar with more cases:
- Cytomegalovirus infection, IBD co-morbidity
- Cytomegaloviral disease
- Infections, IBD-co-morbidities
- Other viral diseases
- Certain infectious and parasitic diseases
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 414 | 182 | 224 |
| Only index persons | 268 | 122 | 146 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.00 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 59.56 | 58.58 | 60.46 |
| Only index persons | 63.16 | 60.88 | 65.06 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 52 | 21 | 31 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.02 |
| Median age at first event (years) | 65.38 | 59.17 | 69.59 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint CMV_PNEUMONIA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CMV_PNEUMONIA | 10.122 [4.72, 21.71] | < 0.001 |
| Birth year | 0.993 [0.98, 1.0] | 0.105 |
During the follow-up period (1.1.1998 — 31.12.2019), 54 out of 114 females with CMV_PNEUMONIA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CMV_PNEUMONIA | 5.501 [3.25, 9.32] | < 0.001 |
| Birth year | 0.984 [0.97, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 55 out of 111 males with CMV_PNEUMONIA died.
Mortality risk
Mortality risk for people of age
years, who have CMV_PNEUMONIA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.989% | 1.02% |
| 5 | 5.265% | 5.537% |
| 10 | 13.387% | 14.094% |
| 15 | 25.115% | 23.732% |
| 20 | 38.525% | 37.855% |
Relationships between endpoints
↥Index endpoint: CMV_PNEUMONIA – Cytomegaloviral pneumonitis
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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