tonsil cancer: Tumors or cancer of the PALATINE TONSIL.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
367 |
4. Check minimum number of eventsNone |
367 |
5. Include endpointsNone |
367 |
6. Filter based on genotype QC (FinnGen only) |
349 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D10
Name in latin
Neoplasma benignum tonsillae palatinae
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Tonsil
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Tonsil
- Benign neoplasm of mouth and pharynx
- Benign neoplasm of mouth and pharynx
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2787 | 1600 | 1173 |
| Only index persons | 2614 | 1535 | 1079 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.05 | 0.03 |
| Only index persons | 0.05 | 0.06 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 56.41 | 55.74 | 57.29 |
| Only index persons | 55.84 | 55.41 | 56.47 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 349 | 203 | 146 |
| Unadjusted period prevalence (%) | 0.08 | 0.08 | 0.07 |
| Median age at first event (years) | 58.86 | 55.70 | 63.26 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_TONSIL and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_TONSIL | 1.132 [0.94, 1.37] | 0.203 |
| Birth year | 0.995 [0.99, 1.0] | 0.236 |
During the follow-up period (1.1.1998 — 31.12.2019), 175 out of 1274 females with CD2_BENIGN_TONSIL died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_TONSIL | 1.917 [1.5, 2.46] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.016 |
During the follow-up period (1.1.1998 — 31.12.2019), 220 out of 943 males with CD2_BENIGN_TONSIL died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_TONSIL.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.13% | 0.355% |
| 5 | 0.709% | 2.208% |
| 10 | 1.835% | 5.227% |
| 15 | 3.23% | 10.463% |
| 20 | 5.62% | 18.211% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_TONSIL – Benign neoplasm: Tonsil
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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