gastric carcinoma: A carcinoma that arises from epithelial cells of the stomach.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
3330 |
4. Check minimum number of eventsNone |
3330 |
5. Include endpointsNone |
3330 |
6. Filter based on genotype QC (FinnGen only) |
3226 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D13
Name in latin
Neoplasma benignum ventriculi
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Stomach
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Stomach
- Benign neoplasm of other and ill-defined parts of digestive system
- Benign neoplasm of other and ill-defined parts of digestive system
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 19792 | 12427 | 7254 |
| Only index persons | 17931 | 11514 | 6417 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.30 | 0.36 | 0.20 |
| Only index persons | 0.36 | 0.42 | 0.24 |
| Median age at first event (years) | |||
| Whole population | 65.96 | 65.50 | 66.71 |
| Only index persons | 65.31 | 64.86 | 66.13 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 3226 | 2058 | 1168 |
| Unadjusted period prevalence (%) | 0.73 | 0.81 | 0.59 |
| Median age at first event (years) | 64.29 | 62.79 | 66.94 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_STOMACH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_STOMACH | 1.275 [1.15, 1.41] | < 0.001 |
| Birth year | 0.993 [0.98, 1.0] | 0.086 |
During the follow-up period (1.1.1998 — 31.12.2019), 2054 out of 10219 females with CD2_BENIGN_STOMACH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_STOMACH | 1.407 [1.25, 1.58] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.008 |
During the follow-up period (1.1.1998 — 31.12.2019), 1717 out of 5767 males with CD2_BENIGN_STOMACH died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_STOMACH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.146% | 0.235% |
| 5 | 0.713% | 1.615% |
| 10 | 1.746% | 4.04% |
| 15 | 3.232% | 7.786% |
| 20 | 5.547% | 13.066% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_STOMACH – Benign neoplasm: Stomach
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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