brain neoplasm: A neoplasm (disease) that involves the brain.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
450 |
4. Check minimum number of eventsNone |
450 |
5. Include endpointsNone |
450 |
6. Filter based on genotype QC (FinnGen only) |
429 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D33
Name in latin
Neoplasma benignum medullae spinalis
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Spinal cord
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Spinal cord
- Benign neoplasm of brain and other parts of central nervous system
- Benign neoplasm of brain and other parts of central nervous system
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2876 | 1502 | 1358 |
| Only index persons | 2586 | 1356 | 1230 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.04 | 0.04 |
| Only index persons | 0.05 | 0.05 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 52.72 | 54.48 | 50.76 |
| Only index persons | 52.31 | 53.93 | 50.53 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 429 | 236 | 193 |
| Unadjusted period prevalence (%) | 0.09 | 0.09 | 0.10 |
| Median age at first event (years) | 53.69 | 52.70 | 54.90 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_SPINAL_CORD and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_SPINAL_CORD | 1.2 [0.99, 1.46] | 0.064 |
| Birth year | 0.996 [0.99, 1.0] | 0.315 |
During the follow-up period (1.1.1998 — 31.12.2019), 142 out of 1100 females with CD2_BENIGN_SPINAL_CORD died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_SPINAL_CORD | 1.165 [0.93, 1.46] | 0.183 |
| Birth year | 0.99 [0.98, 1.0] | 0.045 |
During the follow-up period (1.1.1998 — 31.12.2019), 140 out of 1023 males with CD2_BENIGN_SPINAL_CORD died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_SPINAL_CORD.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.107% | 0.251% |
| 5 | 0.634% | 1.359% |
| 10 | 1.786% | 3.458% |
| 15 | 3.536% | 6.946% |
| 20 | 6.393% | 11.864% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_SPINAL_CORD – Benign neoplasm: Spinal cord
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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