pharynx cancer: A primary or metastatic malignant neoplasm that affects the pharynx.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
236 |
4. Check minimum number of eventsNone |
236 |
5. Include endpointsNone |
236 |
6. Filter based on genotype QC (FinnGen only) |
222 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D10
Name in latin
Neoplasma benignum pharyngis non specificatum
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Pharynx, unspecified
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Pharynx, unspecified
- Benign neoplasm of mouth and pharynx
- Benign neoplasm of mouth and pharynx
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1705 | 921 | 768 |
| Only index persons | 1541 | 851 | 690 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.03 | 0.02 |
| Only index persons | 0.03 | 0.03 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 52.22 | 51.72 | 52.86 |
| Only index persons | 51.94 | 51.56 | 52.40 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 222 | 138 | 84 |
| Unadjusted period prevalence (%) | 0.05 | 0.05 | 0.04 |
| Median age at first event (years) | 55.56 | 54.30 | 57.65 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_PHARYNX_NOS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_PHARYNX_NOS | 1.166 [0.87, 1.55] | 0.296 |
| Birth year | 0.993 [0.98, 1.0] | 0.132 |
During the follow-up period (1.1.1998 — 31.12.2019), 79 out of 643 females with CD2_BENIGN_PHARYNX_NOS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_PHARYNX_NOS | 2.047 [1.56, 2.68] | < 0.001 |
| Birth year | 0.991 [0.98, 1.0] | 0.064 |
During the follow-up period (1.1.1998 — 31.12.2019), 120 out of 559 males with CD2_BENIGN_PHARYNX_NOS died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_PHARYNX_NOS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.078% | 0.443% |
| 5 | 0.59% | 2.697% |
| 10 | 1.432% | 6.434% |
| 15 | 2.974% | 12.222% |
| 20 | 5.547% | 19.808% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_PHARYNX_NOS – Benign neoplasm: Pharynx, unspecified
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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