Malignant Pancreatic Neoplasm: A primary or metastatic malignant tumor involving the pancreas. Representative examples include carcinoma and lymphoma. -- 2003
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
715 |
4. Check minimum number of eventsNone |
715 |
5. Include endpointsNone |
715 |
6. Filter based on genotype QC (FinnGen only) |
701 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D13
Name in latin
Neoplasma benignum pancreatis
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Pancreas
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Pancreas
- Benign neoplasm of other and ill-defined parts of digestive system
- Benign neoplasm of other and ill-defined parts of digestive system
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4049 | 2363 | 1645 |
| Only index persons | 3590 | 2126 | 1464 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.07 | 0.05 |
| Only index persons | 0.07 | 0.08 | 0.06 |
| Median age at first event (years) | |||
| Whole population | 69.61 | 70.03 | 69.18 |
| Only index persons | 69.51 | 69.68 | 69.25 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 701 | 409 | 292 |
| Unadjusted period prevalence (%) | 0.15 | 0.16 | 0.15 |
| Median age at first event (years) | 69.51 | 68.64 | 70.73 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_PANCREAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_PANCREAS | 2.49 [2.03, 3.05] | < 0.001 |
| Birth year | 0.996 [0.99, 1.0] | 0.372 |
During the follow-up period (1.1.1998 — 31.12.2019), 488 out of 1662 females with CD2_BENIGN_PANCREAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_PANCREAS | 3.362 [2.54, 4.46] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.011 |
During the follow-up period (1.1.1998 — 31.12.2019), 427 out of 1130 males with CD2_BENIGN_PANCREAS died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_PANCREAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.271% | 0.774% |
| 5 | 1.715% | 4.164% |
| 10 | 4.112% | 9.607% |
| 15 | 7.39% | 17.252% |
| 20 | 12.905% | 28.711% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_PANCREAS – Benign neoplasm: Pancreas
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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