brain neoplasm: A neoplasm (disease) that involves the brain.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
290 |
4. Check minimum number of eventsNone |
290 |
5. Include endpointsNone |
290 |
6. Filter based on genotype QC (FinnGen only) |
279 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D10
Name in latin
Neoplasma benignum oropharyngis
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Other parts of oropharynx
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Other parts of oropharynx
- Benign neoplasm of mouth and pharynx
- Benign neoplasm of mouth and pharynx
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2025 | 1071 | 939 |
| Only index persons | 1865 | 1002 | 863 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.03 | 0.03 |
| Only index persons | 0.04 | 0.04 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 51.53 | 52.28 | 50.52 |
| Only index persons | 50.66 | 51.48 | 49.72 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 279 | 163 | 116 |
| Unadjusted period prevalence (%) | 0.06 | 0.06 | 0.06 |
| Median age at first event (years) | 54.23 | 52.65 | 56.46 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_OROPHA_OTHER and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_OROPHA_OTHER | 1.256 [0.99, 1.6] | 0.063 |
| Birth year | 0.996 [0.99, 1.01] | 0.452 |
During the follow-up period (1.1.1998 — 31.12.2019), 117 out of 834 females with CD2_BENIGN_OROPHA_OTHER died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_OROPHA_OTHER | 1.677 [1.28, 2.2] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 137 out of 733 males with CD2_BENIGN_OROPHA_OTHER died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_OROPHA_OTHER.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.14% | 0.328% |
| 5 | 0.857% | 1.893% |
| 10 | 2.044% | 4.924% |
| 15 | 3.593% | 9.149% |
| 20 | 6.503% | 14.734% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_OROPHA_OTHER – Benign neoplasm: Other parts of oropharynx
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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