brain neoplasm: A neoplasm (disease) that involves the brain.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
383 |
4. Check minimum number of eventsNone |
383 |
5. Include endpointsNone |
383 |
6. Filter based on genotype QC (FinnGen only) |
366 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D13
Name in latin
Neoplasma benignum oesophagi
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Oesophagus
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Oesophagus
- Benign neoplasm of other and ill-defined parts of digestive system
- Benign neoplasm of other and ill-defined parts of digestive system
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2379 | 1167 | 1194 |
| Only index persons | 2084 | 1051 | 1033 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.03 | 0.03 |
| Only index persons | 0.04 | 0.04 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 61.50 | 61.77 | 61.20 |
| Only index persons | 60.86 | 60.89 | 60.82 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 366 | 193 | 173 |
| Unadjusted period prevalence (%) | 0.08 | 0.08 | 0.09 |
| Median age at first event (years) | 60.88 | 58.60 | 63.43 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_OESOPHAGUS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_OESOPHAGUS | 1.743 [1.42, 2.14] | < 0.001 |
| Birth year | 0.998 [0.99, 1.01] | 0.605 |
During the follow-up period (1.1.1998 — 31.12.2019), 220 out of 904 females with CD2_BENIGN_OESOPHAGUS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_OESOPHAGUS | 2.397 [1.96, 2.94] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 354 out of 951 males with CD2_BENIGN_OESOPHAGUS died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_OESOPHAGUS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.182% | 0.547% |
| 5 | 1.21% | 2.914% |
| 10 | 2.852% | 6.638% |
| 15 | 5.388% | 13.23% |
| 20 | 9.566% | 20.951% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_OESOPHAGUS – Benign neoplasm: Oesophagus
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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