obsolete_meningioma: ['A tumor of meningothelial cells that are manifested in the central nervous system and arise from the arachnoid "cap" cells of the arachnoid villi in the meninges.']
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
513 |
4. Check minimum number of eventsNone |
513 |
5. Include endpointsNone |
513 |
6. Filter based on genotype QC (FinnGen only) |
497 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D32
Name in latin
Neoplasma benignum meningum non specificatarum
Similar endpoints
↥List of similar endpoints to
Beningn neoplasm: Meninges, unspecified
based on the number of shared cases.
Similar with more cases:
- Beningn neoplasm: Meninges, unspecified
- Benign neoplasm of meninges
- Benign neoplasm of meninges
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4723 | 3470 | 1207 |
| Only index persons | 3764 | 2825 | 939 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.08 | 0.10 | 0.03 |
| Only index persons | 0.09 | 0.10 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 67.64 | 68.49 | 64.97 |
| Only index persons | 65.31 | 65.95 | 63.39 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 497 | 359 | 138 |
| Unadjusted period prevalence (%) | 0.12 | 0.14 | 0.07 |
| Median age at first event (years) | 62.47 | 60.60 | 67.34 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_MENINGES_NOS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_MENINGES_NOS | 1.849 [1.64, 2.08] | < 0.001 |
| Birth year | 0.996 [0.99, 1.0] | 0.382 |
During the follow-up period (1.1.1998 — 31.12.2019), 1164 out of 2919 females with CD2_BENIGN_MENINGES_NOS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_MENINGES_NOS | 1.959 [1.64, 2.35] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.033 |
During the follow-up period (1.1.1998 — 31.12.2019), 447 out of 1022 males with CD2_BENIGN_MENINGES_NOS died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_MENINGES_NOS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.178% | 0.389% |
| 5 | 0.971% | 2.184% |
| 10 | 2.724% | 5.914% |
| 15 | 5.12% | 10.892% |
| 20 | 9.169% | 19.39% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_MENINGES_NOS – Beningn neoplasm: Meninges, unspecified
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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