lipoma: A benign, usually painless, well-circumscribed lipomatous tumor composed of adipose tissue.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
10615 |
4. Check minimum number of eventsNone |
10615 |
5. Include endpoints |
11943 |
6. Filter based on genotype QC (FinnGen only) |
11458 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D10-D36
Name in latin
Neoplasma benignum lipomatosum
Similar endpoints
↥List of similar endpoints to
Benign lipomatous neoplasm
based on the number of shared cases.
Similar with more cases:
- Benign lipomatous neoplasm
- Benign neoplasms
- Benign neoplasms
- Neoplasms
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 95153 | 51162 | 43338 |
| Only index persons | 86816 | 47430 | 39386 |
| Unadjusted period prevalence (%) | |||
| Whole population | 1.34 | 1.47 | 1.21 |
| Only index persons | 1.63 | 1.74 | 1.50 |
| Median age at first event (years) | |||
| Whole population | 52.40 | 52.99 | 51.72 |
| Only index persons | 51.66 | 52.34 | 50.84 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 11458 | 6539 | 4919 |
| Unadjusted period prevalence (%) | 2.53 | 2.57 | 2.47 |
| Median age at first event (years) | 53.21 | 52.18 | 54.57 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_LIPOMATOUS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_LIPOMATOUS | 0.93 [0.85, 1.01] | 0.101 |
| Birth year | 0.996 [0.99, 1.01] | 0.373 |
During the follow-up period (1.1.1998 — 31.12.2019), 3530 out of 35467 females with CD2_BENIGN_LIPOMATOUS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_LIPOMATOUS | 0.877 [0.81, 0.95] | 0.002 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 4064 out of 31637 males with CD2_BENIGN_LIPOMATOUS died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_LIPOMATOUS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.063% | 0.159% |
| 5 | 0.513% | 1.004% |
| 10 | 1.457% | 2.559% |
| 15 | 2.702% | 4.584% |
| 20 | 4.825% | 7.763% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_LIPOMATOUS – Benign lipomatous neoplasm
GWS hits: 5
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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