lip cancer: Tumors or cancer of the LIP.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
710 |
4. Check minimum number of eventsNone |
710 |
5. Include endpointsNone |
710 |
6. Filter based on genotype QC (FinnGen only) |
681 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D10
Name in latin
Neoplasma benignum labii (oris)
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Lip
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Lip
- Benign neoplasm of mouth and pharynx
- Benign neoplasm of mouth and pharynx
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5939 | 2865 | 3040 |
| Only index persons | 5167 | 2575 | 2592 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.08 | 0.08 | 0.08 |
| Only index persons | 0.10 | 0.09 | 0.10 |
| Median age at first event (years) | |||
| Whole population | 56.86 | 56.25 | 57.39 |
| Only index persons | 55.08 | 55.45 | 54.71 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 681 | 338 | 343 |
| Unadjusted period prevalence (%) | 0.15 | 0.13 | 0.17 |
| Median age at first event (years) | 59.10 | 55.66 | 62.48 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_LIP and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_LIP | 1.028 [0.9, 1.17] | 0.68 |
| Birth year | 0.996 [0.99, 1.0] | 0.394 |
During the follow-up period (1.1.1998 — 31.12.2019), 393 out of 2264 females with CD2_BENIGN_LIP died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_LIP | 1.101 [0.97, 1.24] | 0.126 |
| Birth year | 0.988 [0.98, 1.0] | 0.021 |
During the follow-up period (1.1.1998 — 31.12.2019), 600 out of 2302 males with CD2_BENIGN_LIP died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_LIP.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.092% | 0.172% |
| 5 | 0.595% | 1.164% |
| 10 | 1.653% | 3.209% |
| 15 | 3.195% | 6.197% |
| 20 | 5.499% | 10.545% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_LIP – Benign neoplasm: Lip
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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