No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1075 |
4. Check minimum number of eventsNone |
1075 |
5. Include endpointsNone |
1075 |
6. Filter based on genotype QC (FinnGen only) |
1045 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D14
Name in latin
Neoplasma benignum laryngis
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Larynx
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Larynx
- Benign neoplasm of middle ear and respiratory system
- Benign neoplasm of middle ear and respiratory system
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 7637 | 2657 | 4895 |
| Only index persons | 6316 | 2327 | 3989 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.12 | 0.08 | 0.14 |
| Only index persons | 0.13 | 0.09 | 0.15 |
| Median age at first event (years) | |||
| Whole population | 55.93 | 55.72 | 55.94 |
| Only index persons | 54.31 | 54.47 | 54.22 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1045 | 338 | 707 |
| Unadjusted period prevalence (%) | 0.28 | 0.13 | 0.36 |
| Median age at first event (years) | 56.32 | 52.05 | 58.36 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_LARYNX and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_LARYNX | 1.44 [1.24, 1.67] | < 0.001 |
| Birth year | 0.999 [0.99, 1.01] | 0.792 |
During the follow-up period (1.1.1998 — 31.12.2019), 365 out of 1646 females with CD2_BENIGN_LARYNX died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_LARYNX | 1.766 [1.57, 1.99] | < 0.001 |
| Birth year | 0.985 [0.97, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 973 out of 3146 males with CD2_BENIGN_LARYNX died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_LARYNX.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.172% | 0.328% |
| 5 | 1.02% | 1.903% |
| 10 | 2.305% | 4.549% |
| 15 | 4.399% | 8.697% |
| 20 | 7.596% | 14.442% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_LARYNX – Benign neoplasm: Larynx
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data