No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1035 |
4. Check minimum number of eventsNone |
1035 |
5. Include endpointsNone |
1035 |
6. Filter based on genotype QC (FinnGen only) |
992 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D30
Name in latin
Neoplasma benignum renis
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Kidney
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Kidney
- Benign neoplasm of urinary organs
- Benign neoplasm of urinary organs
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 6609 | 3971 | 2585 |
| Only index persons | 5892 | 3682 | 2210 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.10 | 0.11 | 0.07 |
| Only index persons | 0.12 | 0.14 | 0.08 |
| Median age at first event (years) | |||
| Whole population | 63.31 | 61.47 | 66.18 |
| Only index persons | 62.69 | 60.74 | 65.94 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 992 | 601 | 391 |
| Unadjusted period prevalence (%) | 0.22 | 0.24 | 0.20 |
| Median age at first event (years) | 61.74 | 58.55 | 66.64 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_KIDNEY and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_KIDNEY | 1.198 [1.05, 1.36] | 0.005 |
| Birth year | 0.993 [0.98, 1.0] | 0.122 |
During the follow-up period (1.1.1998 — 31.12.2019), 525 out of 3055 females with CD2_BENIGN_KIDNEY died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_KIDNEY | 1.35 [1.17, 1.56] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.041 |
During the follow-up period (1.1.1998 — 31.12.2019), 600 out of 1946 males with CD2_BENIGN_KIDNEY died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_KIDNEY.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.095% | 0.245% |
| 5 | 0.589% | 1.509% |
| 10 | 1.686% | 4.136% |
| 15 | 3.282% | 7.802% |
| 20 | 5.995% | 13.486% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_KIDNEY – Benign neoplasm: Kidney
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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