oral cavity cancer: A primary or metastatic malignant neoplasm involving the oral cavity. The majority are squamous cell carcinomas.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
115 |
4. Check minimum number of eventsNone |
115 |
5. Include endpointsNone |
115 |
6. Filter based on genotype QC (FinnGen only) |
111 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D10
Name in latin
Neoplasma benignum basis oris
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Floor of mouth
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Floor of mouth
- Benign neoplasm of mouth and pharynx
- Benign neoplasm of mouth and pharynx
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1059 | 557 | 490 |
| Only index persons | 897 | 489 | 408 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.02 | 0.01 |
| Only index persons | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 53.91 | 54.65 | 52.78 |
| Only index persons | 51.89 | 53.01 | 50.55 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 111 | 55 | 56 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.03 |
| Median age at first event (years) | 53.92 | 54.58 | 53.27 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_FLOOROFMOUTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_FLOOROFMOUTH | 1.587 [1.24, 2.04] | < 0.001 |
| Birth year | 0.996 [0.99, 1.01] | 0.416 |
During the follow-up period (1.1.1998 — 31.12.2019), 117 out of 431 females with CD2_BENIGN_FLOOROFMOUTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_FLOOROFMOUTH | 1.841 [1.37, 2.48] | < 0.001 |
| Birth year | 0.991 [0.98, 1.0] | 0.045 |
During the follow-up period (1.1.1998 — 31.12.2019), 106 out of 342 males with CD2_BENIGN_FLOOROFMOUTH died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_FLOOROFMOUTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.164% | 0.368% |
| 5 | 0.817% | 2.139% |
| 10 | 2.325% | 5.75% |
| 15 | 4.773% | 10.59% |
| 20 | 8.665% | 17.4% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_FLOOROFMOUTH – Benign neoplasm: Floor of mouth
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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