No definition available.
Benign neoplasm: Middle ear, nasal cavity and accessory sinuses
EFO MESH Endpoint Browser PheWeb
CD2_BENIGN_EAR_NASAL_SINUS
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1324 |
4. Check minimum number of eventsNone |
1324 |
5. Include endpointsNone |
1324 |
6. Filter based on genotype QC (FinnGen only) |
1273 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D14
Name in latin
Neoplasma benignum auris mediae
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Middle ear, nasal cavity and accessory sinuses
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Middle ear, nasal cavity and accessory sinuses
- Benign neoplasm of middle ear and respiratory system
- Benign neoplasm of middle ear and respiratory system
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 9658 | 4526 | 5061 |
| Only index persons | 8673 | 4172 | 4501 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.14 | 0.13 | 0.14 |
| Only index persons | 0.16 | 0.15 | 0.17 |
| Median age at first event (years) | |||
| Whole population | 53.85 | 54.43 | 53.29 |
| Only index persons | 52.85 | 53.43 | 52.31 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1273 | 608 | 665 |
| Unadjusted period prevalence (%) | 0.29 | 0.24 | 0.33 |
| Median age at first event (years) | 55.89 | 54.20 | 57.43 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_EAR_NASAL_SINUS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_EAR_NASAL_SINUS | 1.289 [1.13, 1.47] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.221 |
During the follow-up period (1.1.1998 — 31.12.2019), 531 out of 3276 females with CD2_BENIGN_EAR_NASAL_SINUS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_EAR_NASAL_SINUS | 1.197 [0.99, 1.44] | 0.058 |
| Birth year | 0.989 [0.94, 1.04] | 0.691 |
During the follow-up period (1.1.1998 — 31.12.2019), 689 out of 3623 males with CD2_BENIGN_EAR_NASAL_SINUS died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_EAR_NASAL_SINUS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.15% | 0.216% |
| 5 | 0.85% | 1.352% |
| 10 | 2.003% | 3.63% |
| 15 | 3.69% | 6.902% |
| 20 | 6.21% | 11.55% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_EAR_NASAL_SINUS – Benign neoplasm: Middle ear, nasal cavity and accessory sinuses
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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