cranial nerve malignant neoplasm: Benign and malignant neoplasms that arise from one or more of the twelve cranial nerves.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
896 |
4. Check minimum number of eventsNone |
896 |
5. Include endpointsNone |
896 |
6. Filter based on genotype QC (FinnGen only) |
870 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D33
Name in latin
Neoplasma benignum nervi cranialis
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Cranial nerves
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Cranial nerves
- Benign neoplasm of brain and other parts of central nervous system
- Benign neoplasm of brain and other parts of central nervous system
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 6100 | 3369 | 2687 |
| Only index persons | 5447 | 3043 | 2404 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.09 | 0.10 | 0.08 |
| Only index persons | 0.10 | 0.11 | 0.09 |
| Median age at first event (years) | |||
| Whole population | 56.38 | 56.92 | 55.69 |
| Only index persons | 55.98 | 56.46 | 55.36 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 870 | 492 | 378 |
| Unadjusted period prevalence (%) | 0.19 | 0.19 | 0.19 |
| Median age at first event (years) | 56.26 | 55.36 | 57.44 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_CRANIAL_NERVE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_CRANIAL_NERVE | 1.104 [0.96, 1.27] | 0.176 |
| Birth year | 0.997 [0.99, 1.01] | 0.544 |
During the follow-up period (1.1.1998 — 31.12.2019), 312 out of 2291 females with CD2_BENIGN_CRANIAL_NERVE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_CRANIAL_NERVE | 0.893 [0.77, 1.04] | 0.151 |
| Birth year | 0.987 [0.98, 1.0] | 0.008 |
During the follow-up period (1.1.1998 — 31.12.2019), 296 out of 1846 males with CD2_BENIGN_CRANIAL_NERVE died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_CRANIAL_NERVE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.106% | 0.216% |
| 5 | 0.569% | 1.193% |
| 10 | 1.639% | 2.809% |
| 15 | 3.339% | 5.148% |
| 20 | 5.606% | 8.77% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_CRANIAL_NERVE – Benign neoplasm: Cranial nerves
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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