No definition available.
Benign neoplasm: Central nervous system, other parts/unspecified
CD2_BENIGN_CNS_NOS
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
117 |
4. Check minimum number of eventsNone |
117 |
5. Include endpointsNone |
117 |
6. Filter based on genotype QC (FinnGen only) |
111 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D33
Name in latin
Neoplasma benignum alterius partis specificatae systematis nervosi centralis
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Central nervous system, other parts/unspecified
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Central nervous system, other parts/unspecified
- Benign neoplasm of brain and other parts of central nervous system
- Benign neoplasm of brain and other parts of central nervous system
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1132 | 596 | 527 |
| Only index persons | 873 | 465 | 408 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.01 |
| Only index persons | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 48.75 | 50.58 | 46.64 |
| Only index persons | 46.11 | 47.21 | 44.85 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 111 | 54 | 57 |
| Unadjusted period prevalence (%) | 0.03 | 0.02 | 0.03 |
| Median age at first event (years) | 47.97 | 47.53 | 48.38 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_CNS_NOS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_CNS_NOS | 1.387 [1.01, 1.9] | 0.041 |
| Birth year | 1.001 [0.99, 1.01] | 0.808 |
During the follow-up period (1.1.1998 — 31.12.2019), 52 out of 315 females with CD2_BENIGN_CNS_NOS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_CNS_NOS | 1.853 [1.28, 2.68] | 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.022 |
During the follow-up period (1.1.1998 — 31.12.2019), 60 out of 283 males with CD2_BENIGN_CNS_NOS died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_CNS_NOS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.154% | 0.343% |
| 5 | 0.934% | 2.159% |
| 10 | 2.392% | 5.722% |
| 15 | 4.796% | 10.819% |
| 20 | 8.598% | 17.648% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_CNS_NOS – Benign neoplasm: Central nervous system, other parts/unspecified
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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