oropharynx cancer: A primary or metastatic malignant neoplasm that affects the oropharynx.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
414 |
4. Check minimum number of eventsNone |
414 |
5. Include endpointsNone |
414 |
6. Filter based on genotype QC (FinnGen only) |
403 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D14
Name in latin
Neoplasma benignum bronchi
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Bronchus and lung
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Bronchus and lung
- Benign neoplasm of middle ear and respiratory system
- Benign neoplasm of middle ear and respiratory system
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3012 | 1351 | 1630 |
| Only index persons | 2312 | 1123 | 1189 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.04 | 0.05 |
| Only index persons | 0.04 | 0.04 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 57.62 | 56.60 | 58.38 |
| Only index persons | 56.62 | 55.59 | 57.59 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 403 | 169 | 234 |
| Unadjusted period prevalence (%) | 0.10 | 0.07 | 0.12 |
| Median age at first event (years) | 58.08 | 53.97 | 61.04 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_BRONCHUS_LUNG and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_BRONCHUS_LUNG | 1.748 [1.41, 2.17] | < 0.001 |
| Birth year | 0.993 [0.98, 1.0] | 0.142 |
During the follow-up period (1.1.1998 — 31.12.2019), 137 out of 715 females with CD2_BENIGN_BRONCHUS_LUNG died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_BRONCHUS_LUNG | 1.92 [1.6, 2.3] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.072 |
During the follow-up period (1.1.1998 — 31.12.2019), 241 out of 829 males with CD2_BENIGN_BRONCHUS_LUNG died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_BRONCHUS_LUNG.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.114% | 0.359% |
| 5 | 0.91% | 2.593% |
| 10 | 2.427% | 6.229% |
| 15 | 4.365% | 11.649% |
| 20 | 8.005% | 19.781% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_BRONCHUS_LUNG – Benign neoplasm: Bronchus and lung
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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