salivary gland neoplasm: ['Tumors of the SALIVARY GLANDS.']
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
533 |
4. Check minimum number of eventsNone |
533 |
5. Include endpointsNone |
533 |
6. Filter based on genotype QC (FinnGen only) |
514 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D33
Name in latin
Neoplasma benignum cerebri supratentoriale
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Brain, supratentorial
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Brain, supratentorial
- Benign neoplasm of brain and other parts of central nervous system
- Benign neoplasm of brain and other parts of central nervous system
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4145 | 2224 | 1899 |
| Only index persons | 3782 | 2059 | 1723 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.06 | 0.05 |
| Only index persons | 0.07 | 0.08 | 0.07 |
| Median age at first event (years) | |||
| Whole population | 49.48 | 51.35 | 47.25 |
| Only index persons | 48.74 | 50.53 | 46.61 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 514 | 294 | 220 |
| Unadjusted period prevalence (%) | 0.11 | 0.12 | 0.11 |
| Median age at first event (years) | 50.45 | 47.04 | 55.00 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_BRAIN_SUPRATENT and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_BRAIN_SUPRATENT | 1.794 [1.53, 2.1] | < 0.001 |
| Birth year | 1.003 [1.0, 1.01] | 0.441 |
During the follow-up period (1.1.1998 — 31.12.2019), 355 out of 1970 females with CD2_BENIGN_BRAIN_SUPRATENT died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_BRAIN_SUPRATENT | 2.162 [1.81, 2.59] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.09 |
During the follow-up period (1.1.1998 — 31.12.2019), 363 out of 1653 males with CD2_BENIGN_BRAIN_SUPRATENT died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_BRAIN_SUPRATENT.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.206% | 0.378% |
| 5 | 1.309% | 2.719% |
| 10 | 2.936% | 7.058% |
| 15 | 5.921% | 13.53% |
| 20 | 11.166% | 22.667% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_BRAIN_SUPRATENT – Benign neoplasm: Brain, supratentorial
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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