No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
203 |
4. Check minimum number of eventsNone |
203 |
5. Include endpointsNone |
203 |
6. Filter based on genotype QC (FinnGen only) |
193 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D33
Name in latin
Neoplasma benignum cerebri non specificatum
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Brain, unspecified
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Brain, unspecified
- Benign neoplasm of brain and other parts of central nervous system
- Benign neoplasm of brain and other parts of central nervous system
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2424 | 1453 | 938 |
| Only index persons | 1513 | 913 | 600 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.04 | 0.03 |
| Only index persons | 0.03 | 0.03 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 48.74 | 51.26 | 44.54 |
| Only index persons | 42.00 | 45.00 | 37.43 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 193 | 116 | 77 |
| Unadjusted period prevalence (%) | 0.04 | 0.05 | 0.04 |
| Median age at first event (years) | 42.14 | 41.20 | 43.56 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_BRAIN_NOS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_BRAIN_NOS | 1.973 [1.46, 2.67] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.021 |
During the follow-up period (1.1.1998 — 31.12.2019), 87 out of 375 females with CD2_BENIGN_BRAIN_NOS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_BRAIN_NOS | 1.925 [1.33, 2.79] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.015 |
During the follow-up period (1.1.1998 — 31.12.2019), 59 out of 249 males with CD2_BENIGN_BRAIN_NOS died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_BRAIN_NOS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.144% | 0.407% |
| 5 | 1.001% | 2.468% |
| 10 | 2.701% | 5.618% |
| 15 | 4.635% | 10.786% |
| 20 | 7.798% | 17.817% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_BRAIN_NOS – Benign neoplasm: Brain, unspecified
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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