brain neoplasm: A neoplasm (disease) that involves the brain.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
185 |
4. Check minimum number of eventsNone |
185 |
5. Include endpointsNone |
185 |
6. Filter based on genotype QC (FinnGen only) |
178 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Similar endpoints
↥List of similar endpoints to Benign neoplasm: Brain, infratentorial based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Brain, infratentorial
- Benign neoplasm of brain and other parts of central nervous system
- Benign neoplasm of brain and other parts of central nervous system
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 1554 | 828 | 719 |
Only index persons | 1386 | 743 | 643 |
Unadjusted period prevalence (%) | |||
Whole population | 0.02 | 0.02 | 0.02 |
Only index persons | 0.03 | 0.03 | 0.02 |
Median age at first event (years) | |||
Whole population | 44.15 | 46.77 | 40.95 |
Only index persons | 43.19 | 45.75 | 40.23 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 178 | 107 | 71 |
Unadjusted period prevalence (%) | 0.04 | 0.04 | 0.04 |
Median age at first event (years) | 48.30 | 47.53 | 49.46 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_BRAIN_INFRATENT and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
CD2_BENIGN_BRAIN_INFRATENT | 1.861 [1.47, 2.35] | < 0.001 |
Birth year | 0.994 [0.99, 1.0] | 0.201 |
During the follow-up period (1.1.1998 — 31.12.2019), 125 out of 692 females with CD2_BENIGN_BRAIN_INFRATENT died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
CD2_BENIGN_BRAIN_INFRATENT | 2.417 [1.8, 3.24] | < 0.001 |
Birth year | 0.992 [0.98, 1.0] | 0.089 |
During the follow-up period (1.1.1998 — 31.12.2019), 122 out of 603 males with CD2_BENIGN_BRAIN_INFRATENT died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_BRAIN_INFRATENT.N-year risk | Females | Males |
---|---|---|
1 | 0.215% | 0.496% |
5 | 1.161% | 3.052% |
10 | 2.919% | 7.476% |
15 | 5.319% | 14.591% |
20 | 9.131% | 24.239% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_BRAIN_INFRATENT – Benign neoplasm: Brain, infratentorial
GWS hits: -