oral cavity cancer: A primary or metastatic malignant neoplasm involving the oral cavity. The majority are squamous cell carcinomas.
Benign neoplasm: Bones of skull and face
DOID EFO Endpoint Browser PheWeb
CD2_BENIGN_BONE_SKULL_FACE
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
310 |
4. Check minimum number of eventsNone |
310 |
5. Include endpointsNone |
310 |
6. Filter based on genotype QC (FinnGen only) |
301 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Bones of skull and face
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Bones of skull and face
- Benign neoplasm of bone and articular cartilage
- Benign neoplasm of bone and articular cartilage
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2415 | 1490 | 909 |
| Only index persons | 2235 | 1407 | 828 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.04 | 0.03 |
| Only index persons | 0.04 | 0.05 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 44.74 | 46.07 | 42.50 |
| Only index persons | 44.51 | 45.72 | 42.46 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 301 | 224 | 77 |
| Unadjusted period prevalence (%) | 0.08 | 0.09 | 0.04 |
| Median age at first event (years) | 49.64 | 48.73 | 52.29 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_BONE_SKULL_FACE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_BONE_SKULL_FACE | 1.02 [0.82, 1.26] | 0.858 |
| Birth year | 1.001 [0.99, 1.01] | 0.875 |
During the follow-up period (1.1.1998 — 31.12.2019), 106 out of 1100 females with CD2_BENIGN_BONE_SKULL_FACE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_BONE_SKULL_FACE | 0.96 [0.73, 1.26] | 0.769 |
| Birth year | 0.99 [0.98, 1.0] | 0.056 |
During the follow-up period (1.1.1998 — 31.12.2019), 79 out of 659 males with CD2_BENIGN_BONE_SKULL_FACE died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_BONE_SKULL_FACE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.069% | 0.218% |
| 5 | 0.548% | 1.183% |
| 10 | 1.618% | 2.989% |
| 15 | 3.316% | 5.825% |
| 20 | 6.126% | 9.559% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_BONE_SKULL_FACE – Benign neoplasm: Bones of skull and face
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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