No definition available.
Benign neoplasm: Long bones of lower limb
DOID EFO Endpoint Browser PheWeb
CD2_BENIGN_BONE_LONG_LOWER
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1115 |
4. Check minimum number of eventsNone |
1115 |
5. Include endpointsNone |
1115 |
6. Filter based on genotype QC (FinnGen only) |
1081 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D16
Name in latin
Neoplasma benignum ossium longorum membri inferioris
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Long bones of lower limb
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Long bones of lower limb
- Benign neoplasm of bone and articular cartilage
- Benign neoplasm of bone and articular cartilage
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 10196 | 4557 | 5600 |
| Only index persons | 9666 | 4381 | 5285 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.14 | 0.13 | 0.16 |
| Only index persons | 0.18 | 0.16 | 0.20 |
| Median age at first event (years) | |||
| Whole population | 23.26 | 27.03 | 20.08 |
| Only index persons | 23.02 | 26.68 | 19.98 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1081 | 614 | 467 |
| Unadjusted period prevalence (%) | 0.24 | 0.24 | 0.23 |
| Median age at first event (years) | 35.15 | 35.40 | 34.81 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_BONE_LONG_LOWER and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_BONE_LONG_LOWER | 1.158 [0.95, 1.41] | 0.149 |
| Birth year | 0.994 [0.99, 1.0] | 0.166 |
During the follow-up period (1.1.1998 — 31.12.2019), 134 out of 2886 females with CD2_BENIGN_BONE_LONG_LOWER died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_BONE_LONG_LOWER | 1.061 [0.88, 1.28] | 0.529 |
| Birth year | 0.985 [0.98, 0.99] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 164 out of 3257 males with CD2_BENIGN_BONE_LONG_LOWER died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_BONE_LONG_LOWER.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.124% | 0.179% |
| 5 | 0.617% | 1.067% |
| 10 | 1.529% | 2.808% |
| 15 | 3.177% | 5.416% |
| 20 | 5.471% | 9.13% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_BONE_LONG_LOWER – Benign neoplasm: Long bones of lower limb
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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