No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
320 |
4. Check minimum number of eventsNone |
320 |
5. Include endpointsNone |
320 |
6. Filter based on genotype QC (FinnGen only) |
310 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D12
Name in latin
Neoplasma benignum appendicis vermiformis
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Appendix
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Appendix
- Benign neoplasm: Colon
- Benign neoplasm: Colon
- Benign neoplasm of colon, rectum, anus and anal canal
- Benign neoplasm of colon, rectum, anus and anal canal
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2109 | 1194 | 910 |
| Only index persons | 1983 | 1129 | 854 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.03 | 0.03 |
| Only index persons | 0.04 | 0.04 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 65.07 | 63.69 | 66.86 |
| Only index persons | 64.78 | 63.24 | 66.80 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 310 | 170 | 140 |
| Unadjusted period prevalence (%) | 0.07 | 0.07 | 0.07 |
| Median age at first event (years) | 65.98 | 63.61 | 68.86 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_APPENDIX and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_APPENDIX | 1.145 [0.93, 1.41] | 0.206 |
| Birth year | 0.999 [0.99, 1.01] | 0.73 |
During the follow-up period (1.1.1998 — 31.12.2019), 186 out of 979 females with CD2_BENIGN_APPENDIX died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_APPENDIX | 1.264 [1.04, 1.54] | 0.019 |
| Birth year | 0.984 [0.97, 0.99] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 219 out of 743 males with CD2_BENIGN_APPENDIX died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_APPENDIX.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.116% | 0.274% |
| 5 | 0.71% | 1.536% |
| 10 | 1.883% | 3.573% |
| 15 | 3.424% | 6.429% |
| 20 | 5.936% | 10.78% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_APPENDIX – Benign neoplasm: Appendix
GWS hits: 3
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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