Campylobacter enteritis

CAMPYLOENTERITIS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 A04.5
  • Hospital discharge: ICD-9 0084E
  • Cause of death: ICD-10 A04.5
  • Cause of death: ICD-9 0084E

2 out of 7 registries used, show all original rules.

894

4. Check minimum number of events

None

894

5. Include endpoints

None

894

6. Filter based on genotype QC (FinnGen only)

850

Control definitions (FinnGen only)

Control exclude IBD_BACT_INTEST_INFECTIONS

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 A04
Name in latin Enteritis campylobacterialis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 6934 3062 3832
Only index persons 6408 2845 3563
Unadjusted period prevalence (%)
Whole population 0.10 0.09 0.11
Only index persons 0.12 0.10 0.14
Median age at first event (years)
Whole population 46.13 46.05 46.04
Only index persons 44.90 44.55 45.18

-FinnGen-

Key figures

All Female Male
Number of individuals 850 429 421
Unadjusted period prevalence (%) 0.19 0.17 0.21
Median age at first event (years) 51.19 47.48 54.97

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Association

Association between endpoint CAMPYLOENTERITIS and mortality.

Females

Parameter HR [95% CI] p-value
CAMPYLOENTERITIS 1.153 [0.98, 1.35] 0.078
Birth year 0.995 [0.99, 1.0] 0.213

During the follow-up period (1.1.1998 — 31.12.2019), 278 out of 2315 females with CAMPYLOENTERITIS died.

Males

Parameter HR [95% CI] p-value
CAMPYLOENTERITIS 1.03 [0.89, 1.19] 0.694
Birth year 0.99 [0.98, 1.0] 0.059

During the follow-up period (1.1.1998 — 31.12.2019), 344 out of 2843 males with CAMPYLOENTERITIS died.

Mortality risk

Mortality risk for people of age

years, who have CAMPYLOENTERITIS.

N-year risk Females Males
1 0.103% 0.225%
5 0.704% 1.39%
10 1.658% 3.461%
15 3.356% 6.371%
20 5.84% 10.663%

Relationships between endpoints

Index endpoint: CAMPYLOENTERITIS – Campylobacter enteritis

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data