No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
|
1. Apply sex-specific ruleNone |
- |
2. Check conditionsNone |
|
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpointsNone |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
Control exclude
C3_CANCER, C3_CANCER_WIDE
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF9
Similar endpoints
↥List of similar endpoints to
Malignant neoplasm of thymus
based on the number of shared cases.
Similar with more cases:
- Malignant neoplasm of thymus
- Malignant neoplasm of respiratory system and intrathoracic organs
- Malignant neoplasm of respiratory system and intrathoracic organs
- Malignant neoplasm
- Malignant neoplasm
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 483 | 227 | 250 |
| Only index persons | 342 | 173 | 169 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 61.12 | 60.06 | 61.87 |
| Only index persons | 63.13 | 62.96 | 63.31 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 93 | 41 | 52 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.03 |
| Median age at first event (years) | 61.31 | 58.63 | 63.41 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint C3_THYMUS_EXALLC and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| C3_THYMUS_EXALLC | 5.399 [3.12, 9.35] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.032 |
During the follow-up period (1.1.1998 — 31.12.2019), 56 out of 154 males with C3_THYMUS_EXALLC died.
Mortality risk
Mortality risk for people of age
years, who have C3_THYMUS_EXALLC.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.896% |
| 5 | No data | 6.078% |
| 10 | No data | 15.092% |
| 15 | No data | 27.97% |
| 20 | No data | 43.676% |
Relationships between endpoints
↥Index endpoint: C3_THYMUS_EXALLC – Malignant neoplasm of thymus
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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