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Malignant neoplasm, without specification of site

DOID Endpoint Browser

C3_SECONDARY_WITHOUT_SITESPEC

cancer: A tumor composed of atypical neoplastic, often pleomorphic cells that invade other tissues. Malignant neoplasms often metastasize to distant anatomic sites and may recur after excision. The most common malignant neoplasms are carcinomas (adenocarcinomas or squamous cell carcinomas), Hodgkin and non-Hodgkin lymphomas, leukemias, melanomas, and sarcomas.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 — C80
  • Cause of death: ICD-9 — 199
  • Cause of death: ICD-8 — 199
  • Cancer registry: Topography ICD-O-3 — C80
  • Cancer registry: Morphology ICD-O-3 — ANY
  • Cancer registry: Behaviour codes — 3

2 out of 7 registries used, show all original rules.

1122

4. Check minimum number of events

None

1122

5. Include endpoints

None

1122

6. Filter based on genotype QC (FinnGen only)

1088

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF9

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 1088 391 697
Unadjusted period prevalence (%) 0.28 0.15 0.35
Median age at first event (years) 71.78 70.26 72.63

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

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This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

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Index endpoint: C3_SECONDARY_WITHOUT_SITESPEC – Malignant neoplasm, without specification of site

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).