No definition available.
Neuroendocrine tumor and carcinoma of pancreas
C3_PANCREAS_NEUROENDOCRINE_EXALLC
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
|
1. Apply sex-specific ruleNone |
- |
2. Check conditionsNone |
|
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpointsNone |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
Control exclude
C3_CANCER, C3_CANCER_WIDE
Extra metadata
First used in FinnGen datafreeze
DF8
Similar endpoints
↥List of similar endpoints to
Neuroendocrine tumor and carcinoma of pancreas
based on the number of shared cases.
Similar with more cases:
- Neuroendocrine tumor and carcinoma of pancreas
- Malignant neoplasm of pancreas
- Malignant neoplasm of pancreas
- Malignant neoplasm of digestive organs
- Malignant neoplasm of digestive organs
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 851 | 417 | 428 |
| Only index persons | 724 | 362 | 362 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 63.08 | 62.39 | 63.77 |
| Only index persons | 62.77 | 61.92 | 63.62 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 169 | 81 | 88 |
| Unadjusted period prevalence (%) | 0.04 | 0.03 | 0.04 |
| Median age at first event (years) | 60.20 | 57.62 | 62.58 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint C3_PANCREAS_NEUROENDOCRINE_EXALLC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| C3_PANCREAS_NEUROENDOCRINE_EXALLC | 6.893 [4.67, 10.18] | < 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.519 |
During the follow-up period (1.1.1998 — 31.12.2019), 133 out of 341 females with C3_PANCREAS_NEUROENDOCRINE_EXALLC died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| C3_PANCREAS_NEUROENDOCRINE_EXALLC | 6.688 [4.16, 10.76] | < 0.001 |
| Birth year | 0.983 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 143 out of 345 males with C3_PANCREAS_NEUROENDOCRINE_EXALLC died.
Mortality risk
Mortality risk for people of age
years, who have C3_PANCREAS_NEUROENDOCRINE_EXALLC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.669% | 1.281% |
| 5 | 4.301% | 7.728% |
| 10 | 10.206% | 16.913% |
| 15 | 19.23% | 28.921% |
| 20 | 32.028% | 45.297% |
Relationships between endpoints
↥Index endpoint: C3_PANCREAS_NEUROENDOCRINE_EXALLC – Neuroendocrine tumor and carcinoma of pancreas
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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