No definition available.
Adenocarcinoma and Papillary adenocarcinoma of kidney
C3_KIDNEY_PAPILLARYADENO_EXALLC
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
|
1. Apply sex-specific ruleNone |
- |
2. Check conditionsNone |
|
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpointsNone |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
Control exclude
C3_CANCER, C3_CANCER_WIDE
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF9
Similar endpoints
↥List of similar endpoints to
Adenocarcinoma and Papillary adenocarcinoma of kidney
based on the number of shared cases.
Similar with more cases:
- Adenocarcinoma and Papillary adenocarcinoma of kidney
- Malignant neoplasm of kidney, except renal pelvis
- Malignant neoplasm of kidney, except renal pelvis
- Malignant neoplasm of urinary organs
- Malignant neoplasm of urinary organs
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1451 | 360 | 1087 |
| Only index persons | 1319 | 332 | 987 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.01 | 0.03 |
| Only index persons | 0.03 | 0.01 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 67.00 | 68.67 | 66.47 |
| Only index persons | 67.06 | 68.67 | 66.52 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 303 | 74 | 229 |
| Unadjusted period prevalence (%) | 0.09 | 0.03 | 0.12 |
| Median age at first event (years) | 67.03 | 67.69 | 66.82 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint C3_KIDNEY_PAPILLARYADENO_EXALLC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| C3_KIDNEY_PAPILLARYADENO_EXALLC | 3.004 [2.18, 4.14] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.261 |
During the follow-up period (1.1.1998 — 31.12.2019), 93 out of 291 females with C3_KIDNEY_PAPILLARYADENO_EXALLC died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| C3_KIDNEY_PAPILLARYADENO_EXALLC | 2.133 [1.65, 2.75] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.024 |
During the follow-up period (1.1.1998 — 31.12.2019), 267 out of 916 males with C3_KIDNEY_PAPILLARYADENO_EXALLC died.
Mortality risk
Mortality risk for people of age
years, who have C3_KIDNEY_PAPILLARYADENO_EXALLC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.237% | 0.437% |
| 5 | 1.818% | 2.686% |
| 10 | 4.126% | 6.426% |
| 15 | 8.038% | 11.856% |
| 20 | 14.133% | 19.765% |
Relationships between endpoints
↥Index endpoint: C3_KIDNEY_PAPILLARYADENO_EXALLC – Adenocarcinoma and Papillary adenocarcinoma of kidney
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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