No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
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Phenotype data |
|
1. Apply sex-specific ruleNone |
- |
2. Check conditionsNone |
|
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
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5. Include endpointsNone |
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6. Filter based on genotype QC (FinnGen only)None |
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Control definitions (FinnGen only)
Extra metadata
Similar endpoints
↥List of similar endpoints to Malignant neoplasm of eye and adnexa based on the number of shared cases.
Similar with more cases:
- Malignant neoplasm of eye and adnexa
- Malignant neoplasm of eye, brain and central nervous system
- Malignant neoplasm of eye, brain and central nervous system
- Malignant neoplasm
- Malignant neoplasm
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 2814 | 1357 | 1408 |
Only index persons | 1753 | 884 | 869 |
Unadjusted period prevalence (%) | |||
Whole population | 0.04 | 0.04 | 0.04 |
Only index persons | 0.03 | 0.03 | 0.03 |
Median age at first event (years) | |||
Whole population | 59.78 | 59.91 | 59.58 |
Only index persons | 59.31 | 60.12 | 58.49 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 256 | 120 | 136 |
Unadjusted period prevalence (%) | 0.06 | 0.05 | 0.07 |
Median age at first event (years) | 60.19 | 58.68 | 61.52 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint C3_EYE_ADNEXA_EXALLC and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
C3_EYE_ADNEXA_EXALLC | 2.649 [2.12, 3.3] | < 0.001 |
Birth year | 0.992 [0.98, 1.0] | 0.082 |
During the follow-up period (1.1.1998 — 31.12.2019), 279 out of 682 females with C3_EYE_ADNEXA_EXALLC died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
C3_EYE_ADNEXA_EXALLC | 2.222 [1.72, 2.86] | < 0.001 |
Birth year | 0.983 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 330 out of 728 males with C3_EYE_ADNEXA_EXALLC died.
Mortality risk
Mortality risk for people of age
years, who have C3_EYE_ADNEXA_EXALLC.N-year risk | Females | Males |
---|---|---|
1 | 0.17% | 0.402% |
5 | 1.452% | 1.995% |
10 | 3.479% | 5.253% |
15 | 6.5% | 9.999% |
20 | 11.715% | 16.957% |
Relationships between endpoints
↥Index endpoint: C3_EYE_ADNEXA_EXALLC – Malignant neoplasm of eye and adnexa
GWS hits: 1