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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart C3_AML_EXALLC for full statistics.

Acute myeloid leukaemia

DOID Endpoint Browser

C3_AML

acute myeloid leukemia: Acute myeloid leukemia (AML) is a group of neoplasms arising from precursor cells committed to the myeloid cell-line differentiation. All of them are characterized by clonal expansion of myeloid blasts. AML manifests by fever, pallor, anemia, hemorrhages and recurrent infections.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

  • HLP_C3_AML
359

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 — C92.0
  • Cause of death: ICD-9 — 2050A
  • Cause of death: ICD-8 — 20500
  • Cancer registry: Topography ICD-O-3 — ANY
  • Cancer registry: Morphology ICD-O-3 — 9840|9861|986[67]|987[1-4]|989[1567]|9910|9920|993[01]
  • Cancer registry: Behaviour codes — 3

2 out of 7 registries used, show all original rules.

359

4. Check minimum number of events

None

359

5. Include endpoints

359

6. Filter based on genotype QC (FinnGen only)

321

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF8

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 321 130 191
Unadjusted period prevalence (%) 0.08 0.05 0.10
Median age at first event (years) 66.10 59.15 70.83

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

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This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

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Index endpoint: C3_AML – Acute myeloid leukaemia

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).