Viral infections of central nervous system, not elsewhere classified/unspecified

AB1_VIRAN_CNS_INFECTIONS_NOS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 A88, A89
  • Hospital discharge: ICD-9 04[6|9]
  • Hospital discharge: ICD-8 04[6]
  • Cause of death: ICD-10 A88, A89
  • Cause of death: ICD-9 04[6|9]
  • Cause of death: ICD-8 04[6]

2 out of 7 registries used, show all original rules.

384

4. Check minimum number of events

None

384

5. Include endpoints

None

384

6. Filter based on genotype QC (FinnGen only)

375

Control definitions (FinnGen only)

Control exclude AB1_VIRAL_CNS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3558 1691 1843
Only index persons 3046 1465 1581
Unadjusted period prevalence (%)
Whole population 0.05 0.05 0.05
Only index persons 0.06 0.05 0.06
Median age at first event (years)
Whole population 27.63 30.29 24.76
Only index persons 25.73 28.93 22.76

-FinnGen-

Key figures

All Female Male
Number of individuals 375 215 160
Unadjusted period prevalence (%) 0.08 0.08 0.08
Median age at first event (years) 29.06 30.34 27.34

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

Mortality – FinRegistry

Association

Association between endpoint AB1_VIRAN_CNS_INFECTIONS_NOS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have AB1_VIRAN_CNS_INFECTIONS_NOS.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: AB1_VIRAN_CNS_INFECTIONS_NOS – Viral infections of central nervous system, not elsewhere classified/unspecified

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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