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Viral warts

EFO Endpoint Browser PheWeb

AB1_VIRAL_WARTS

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — B07
  • Hospital discharge: ICD-9 — 0781[A|B]
  • Hospital discharge: ICD-8 — 051
  • Cause of death: ICD-10 — B07
  • Cause of death: ICD-9 — 0781[A|B]
  • Cause of death: ICD-8 — 051

2 out of 7 registries used, show all original rules.

3785

4. Check minimum number of events

None

3785

5. Include endpoints

None

3785

6. Filter based on genotype QC (FinnGen only)

3644

Control definitions (FinnGen only)

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF5

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 32087 17465 14527
Only index persons 29396 16155 13241
Unadjusted period prevalence (%)
Whole population 0.46 0.50 0.41
Only index persons 0.55 0.59 0.51
Median age at first event (years)
Whole population 29.73 31.02 28.13
Only index persons 31.93 33.28 30.29

-FinnGen-

Key figures

All Female Male
Number of individuals 3644 2227 1417
Unadjusted period prevalence (%) 0.81 0.87 0.71
Median age at first event (years) 43.77 40.54 48.85

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Association

Association between endpoint AB1_VIRAL_WARTS and mortality.

Females

Parameter HR [95% CI] p-value
AB1_VIRAL_WARTS 1.202 [1.07, 1.35] 0.002
Birth year 0.995 [0.99, 1.0] 0.243

During the follow-up period (1.1.1998 — 31.12.2019), 1093 out of 14218 females with AB1_VIRAL_WARTS died.

Males

Parameter HR [95% CI] p-value
AB1_VIRAL_WARTS 1.296 [1.15, 1.46] < 0.001
Birth year 0.989 [0.98, 1.0] 0.023

During the follow-up period (1.1.1998 — 31.12.2019), 1218 out of 11183 males with AB1_VIRAL_WARTS died.

Mortality risk

Mortality risk for people of age

years, who have AB1_VIRAL_WARTS.

N-year risk Females Males
1 0.114% 0.326%
5 0.778% 1.597%
10 1.725% 3.805%
15 3.462% 7.096%
20 6.028% 12.467%

Relationships between endpoints

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Index endpoint: AB1_VIRAL_WARTS – Viral warts

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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