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Viral conjunctivitis

EFO Endpoint Browser PheWeb

AB1_VIRAAL_CONJUNCT

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — B30
  • Hospital discharge: ICD-9 — 07[7]
  • Hospital discharge: ICD-8 — 07[8]
  • Cause of death: ICD-10 — B30
  • Cause of death: ICD-9 — 07[7]
  • Cause of death: ICD-8 — 07[8]

2 out of 7 registries used, show all original rules.

705

4. Check minimum number of events

None

705

5. Include endpoints

None

705

6. Filter based on genotype QC (FinnGen only)

673

Control definitions (FinnGen only)

Control exclude AB1_OTHER_VIRAL

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF5

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 6693 3672 2988
Only index persons 6103 3418 2685
Unadjusted period prevalence (%)
Whole population 0.10 0.11 0.08
Only index persons 0.12 0.13 0.10
Median age at first event (years)
Whole population 32.92 35.43 29.78
Only index persons 34.62 36.51 32.22

-FinnGen-

Key figures

All Female Male
Number of individuals 673 447 226
Unadjusted period prevalence (%) 0.15 0.18 0.11
Median age at first event (years) 41.82 40.94 43.58

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Association

Association between endpoint AB1_VIRAAL_CONJUNCT and mortality.

Females

Parameter HR [95% CI] p-value
AB1_VIRAAL_CONJUNCT 1.087 [0.87, 1.35] 0.453
Birth year 0.995 [0.99, 1.0] 0.218

During the follow-up period (1.1.1998 — 31.12.2019), 135 out of 3306 females with AB1_VIRAAL_CONJUNCT died.

Males

Parameter HR [95% CI] p-value
AB1_VIRAAL_CONJUNCT 1.091 [0.88, 1.35] 0.432
Birth year 0.989 [0.98, 1.0] 0.026

During the follow-up period (1.1.1998 — 31.12.2019), 130 out of 2559 males with AB1_VIRAAL_CONJUNCT died.

Mortality risk

Mortality risk for people of age

years, who have AB1_VIRAAL_CONJUNCT.

N-year risk Females Males
1 0.102% 0.262%
5 0.715% 1.337%
10 1.664% 3.385%
15 3.117% 6.616%
20 5.533% 10.786%

Relationships between endpoints

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Index endpoint: AB1_VIRAAL_CONJUNCT – Viral conjunctivitis

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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