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Tick-borne viral encephalitis

EFO Endpoint Browser PheWeb

AB1_TICK_BORNE_ENCEPHALITIS

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — A84
  • Hospital discharge: ICD-9 — 06[3]
  • Hospital discharge: ICD-8 — 06[3]
  • Cause of death: ICD-10 — A84
  • Cause of death: ICD-9 — 06[3]
  • Cause of death: ICD-8 — 06[3]

2 out of 7 registries used, show all original rules.

118

4. Check minimum number of events

None

118

5. Include endpoints

None

118

6. Filter based on genotype QC (FinnGen only)

110

Control definitions (FinnGen only)

Control exclude AB1_VIRAL_CNS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF5

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1177 458 710
Only index persons 1085 435 650
Unadjusted period prevalence (%)
Whole population 0.02 0.01 0.02
Only index persons 0.02 0.02 0.02
Median age at first event (years)
Whole population 49.62 50.46 48.87
Only index persons 50.10 50.59 49.77

-FinnGen-

Key figures

All Female Male
Number of individuals 110 56 54
Unadjusted period prevalence (%) 0.02 0.02 0.03
Median age at first event (years) 55.09 54.03 56.17

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

Mortality – FinRegistry

↥

Association

Association between endpoint AB1_TICK_BORNE_ENCEPHALITIS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have AB1_TICK_BORNE_ENCEPHALITIS.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

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Index endpoint: AB1_TICK_BORNE_ENCEPHALITIS – Tick-borne viral encephalitis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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