No definition available.
Streptococcus and staphylococcus as the cause of diseases classified to other chapters
AB1_STREPTSTAPHYCOCC_INOTHER
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
195 |
4. Check minimum number of eventsNone |
195 |
5. Include endpointsNone |
195 |
6. Filter based on genotype QC (FinnGen only) |
185 |
Control definitions (FinnGen only)
Control exclude
AB1_BACT_BIR_OTHER_INF_AGENTS
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5
Similar endpoints
↥List of similar endpoints to
Streptococcus and staphylococcus as the cause of diseases classified to other chapters
based on the number of shared cases.
Similar with more cases:
- Bacterial, viral and other infectious agents
- Certain infectious and parasitic diseases
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2560 | 1085 | 1457 |
| Only index persons | 1924 | 822 | 1102 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.03 | 0.04 |
| Only index persons | 0.04 | 0.03 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 38.73 | 37.89 | 39.06 |
| Only index persons | 40.34 | 40.80 | 39.99 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 185 | 74 | 111 |
| Unadjusted period prevalence (%) | 0.05 | 0.03 | 0.06 |
| Median age at first event (years) | 56.10 | 54.83 | 56.95 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint AB1_STREPTSTAPHYCOCC_INOTHER and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_STREPTSTAPHYCOCC_INOTHER | 2.548 [1.94, 3.35] | < 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.489 |
During the follow-up period (1.1.1998 — 31.12.2019), 185 out of 872 females with AB1_STREPTSTAPHYCOCC_INOTHER died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_STREPTSTAPHYCOCC_INOTHER | 3.059 [2.4, 3.9] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 310 out of 1147 males with AB1_STREPTSTAPHYCOCC_INOTHER died.
Mortality risk
Mortality risk for people of age
years, who have AB1_STREPTSTAPHYCOCC_INOTHER.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.3% | 0.628% |
| 5 | 1.742% | 3.201% |
| 10 | 4.149% | 8.239% |
| 15 | 7.55% | 15.117% |
| 20 | 13.582% | 24.671% |
Relationships between endpoints
↥Index endpoint: AB1_STREPTSTAPHYCOCC_INOTHER – Streptococcus and staphylococcus as the cause of diseases classified to other chapters
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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