No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
698 |
4. Check minimum number of eventsNone |
698 |
5. Include endpointsNone |
698 |
6. Filter based on genotype QC (FinnGen only) |
667 |
Control definitions (FinnGen only)
Control exclude
AB1_SEQULEAE_OF_INFECTIONS_AND_PARASITES
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5
Similar endpoints
↥List of similar endpoints to
Sequelae of tuberculosis
based on the number of shared cases.
Similar with more cases:
- Sequelae of infectious and parasitic diseases
- Certain infectious and parasitic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 12957 | 5086 | 7338 |
| Only index persons | 5957 | 2950 | 3007 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.20 | 0.15 | 0.21 |
| Only index persons | 0.11 | 0.11 | 0.11 |
| Median age at first event (years) | |||
| Whole population | 67.14 | 68.05 | 66.71 |
| Only index persons | 66.85 | 67.27 | 66.43 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 667 | 236 | 431 |
| Unadjusted period prevalence (%) | 0.17 | 0.09 | 0.22 |
| Median age at first event (years) | 66.21 | 63.02 | 67.95 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint AB1_SEQULAE_TUBERCU and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_SEQULAE_TUBERCU | 1.853 [1.65, 2.08] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.197 |
During the follow-up period (1.1.1998 — 31.12.2019), 1167 out of 2052 females with AB1_SEQULAE_TUBERCU died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_SEQULAE_TUBERCU | 1.985 [1.74, 2.26] | < 0.001 |
| Birth year | 0.985 [0.98, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 1711 out of 2517 males with AB1_SEQULAE_TUBERCU died.
Mortality risk
Mortality risk for people of age
years, who have AB1_SEQULAE_TUBERCU.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.13% | 0.327% |
| 5 | 0.906% | 2.259% |
| 10 | 2.454% | 5.349% |
| 15 | 4.857% | 10.109% |
| 20 | 8.247% | 17.206% |
Relationships between endpoints
↥Index endpoint: AB1_SEQULAE_TUBERCU – Sequelae of tuberculosis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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