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Other superficial mycoses

EFO Endpoint Browser PheWeb

AB1_OTHER_SUPERF_MYCOSIS

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — B36
  • Hospital discharge: ICD-9 — 111
  • Hospital discharge: ICD-8 — 111
  • Cause of death: ICD-10 — B36
  • Cause of death: ICD-9 — 111
  • Cause of death: ICD-8 — 111

2 out of 7 registries used, show all original rules.

676

4. Check minimum number of events

None

676

5. Include endpoints

None

676

6. Filter based on genotype QC (FinnGen only)

650

Control definitions (FinnGen only)

Control exclude AB1_MYCOSES

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF5

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5932 2806 3076
Only index persons 5363 2569 2794
Unadjusted period prevalence (%)
Whole population 0.08 0.08 0.09
Only index persons 0.10 0.09 0.11
Median age at first event (years)
Whole population 38.43 39.96 37.05
Only index persons 37.82 39.40 36.37

-FinnGen-

Key figures

All Female Male
Number of individuals 650 325 325
Unadjusted period prevalence (%) 0.15 0.13 0.16
Median age at first event (years) 43.72 42.23 45.21

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Association

Association between endpoint AB1_OTHER_SUPERF_MYCOSIS and mortality.

Females

Parameter HR [95% CI] p-value
AB1_OTHER_SUPERF_MYCOSIS 1.458 [1.17, 1.82] < 0.001
Birth year 0.993 [0.98, 1.0] 0.101

During the follow-up period (1.1.1998 — 31.12.2019), 162 out of 1804 females with AB1_OTHER_SUPERF_MYCOSIS died.

Males

Parameter HR [95% CI] p-value
AB1_OTHER_SUPERF_MYCOSIS 1.789 [1.46, 2.2] < 0.001
Birth year 0.986 [0.98, 1.0] 0.005

During the follow-up period (1.1.1998 — 31.12.2019), 270 out of 1925 males with AB1_OTHER_SUPERF_MYCOSIS died.

Mortality risk

Mortality risk for people of age

years, who have AB1_OTHER_SUPERF_MYCOSIS.

N-year risk Females Males
1 0.135% 0.398%
5 0.8% 2.169%
10 2.085% 5.0%
15 4.018% 9.478%
20 7.086% 15.894%

Relationships between endpoints

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Index endpoint: AB1_OTHER_SUPERF_MYCOSIS – Other superficial mycoses

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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