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Other mycoses, not elsewhere classified/unspecified

Endpoint Browser PheWeb

AB1_MYSOSIS_NOS

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — B48, B49
  • Hospital discharge: ICD-9 — 11[7-9]
  • Hospital discharge: ICD-8 — 117
  • Hospital discharge: excluded ICD-9 — 117[1-5]
  • Hospital discharge: excluded ICD-8 — 117[1-3]
  • Cause of death: ICD-10 — B48, B49
  • Cause of death: ICD-9 — 11[7-9]
  • Cause of death: ICD-8 — 117
  • Cause of death: excluded ICD-9 — 117[1-5]
  • Cause of death: excluded ICD-8 — 117[1-3]

2 out of 7 registries used, show all original rules.

88

4. Check minimum number of events

None

88

5. Include endpoints

None

88

6. Filter based on genotype QC (FinnGen only)

86

Control definitions (FinnGen only)

Control exclude AB1_MYCOSES

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF5

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1022 457 554
Only index persons 724 330 394
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.02
Only index persons 0.01 0.01 0.02
Median age at first event (years)
Whole population 56.38 57.52 55.64
Only index persons 53.71 56.31 51.53

-FinnGen-

Key figures

All Female Male
Number of individuals 86 38 48
Unadjusted period prevalence (%) 0.02 0.01 0.02
Median age at first event (years) 60.20 52.88 66.00

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

Mortality – FinRegistry

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Association

Association between endpoint AB1_MYSOSIS_NOS and mortality.

Females

Parameter HR [95% CI] p-value
AB1_MYSOSIS_NOS 4.838 [2.52, 9.31] < 0.001
Birth year 0.991 [0.98, 1.0] 0.043

During the follow-up period (1.1.1998 — 31.12.2019), 86 out of 207 females with AB1_MYSOSIS_NOS died.

Males

Parameter HR [95% CI] p-value
AB1_MYSOSIS_NOS 4.742 [2.8, 8.04] < 0.001
Birth year 0.986 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 94 out of 240 males with AB1_MYSOSIS_NOS died.

Mortality risk

Mortality risk for people of age

years, who have AB1_MYSOSIS_NOS.

N-year risk Females Males
1 0.397% 1.023%
5 2.369% 4.884%
10 6.124% 12.269%
15 11.84% 22.656%
20 19.31% 36.018%

Relationships between endpoints

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Index endpoint: AB1_MYSOSIS_NOS – Other mycoses, not elsewhere classified/unspecified

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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