No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
146 |
4. Check minimum number of eventsNone |
146 |
5. Include endpointsNone |
146 |
6. Filter based on genotype QC (FinnGen only) |
133 |
Control definitions (FinnGen only)
Control exclude
AB1_VIRAL_HEPATITIS
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
B15-B19
Name in latin
Hepatitis B acuta
Similar endpoints
↥List of similar endpoints to
Acute hepatitis B
based on the number of shared cases.
Similar with more cases:
- Acute hepatitis B
- Viral hepatitis, IBD co-morbidity
- Viral hepatitis
- Certain infectious and parasitic diseases
- Any operation in hilmo
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1640 | 629 | 974 |
| Only index persons | 1328 | 541 | 787 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.03 |
| Only index persons | 0.03 | 0.02 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 30.79 | 27.28 | 32.85 |
| Only index persons | 30.02 | 26.63 | 32.34 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 133 | 66 | 67 |
| Unadjusted period prevalence (%) | 0.03 | 0.03 | 0.03 |
| Median age at first event (years) | 31.71 | 28.18 | 35.18 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint AB1_HEPATITIS_B and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_HEPATITIS_B | 3.56 [2.5, 5.06] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.011 |
During the follow-up period (1.1.1998 — 31.12.2019), 128 out of 555 males with AB1_HEPATITIS_B died.
Mortality risk
Mortality risk for people of age
years, who have AB1_HEPATITIS_B.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.522% |
| 5 | No data | 4.322% |
| 10 | No data | 10.091% |
| 15 | No data | 17.924% |
| 20 | No data | 29.368% |
Relationships between endpoints
↥Index endpoint: AB1_HEPATITIS_B – Acute hepatitis B
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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