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Cholera

EFO Endpoint Browser PheWeb

AB1_CHOLERA

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — A00
  • Hospital discharge: ICD-9 — 00[1]
  • Hospital discharge: ICD-8 — 00[0]
  • Cause of death: ICD-10 — A00
  • Cause of death: ICD-9 — 00[1]
  • Cause of death: ICD-8 — 00[0]

2 out of 7 registries used, show all original rules.

1516

4. Check minimum number of events

None

1516

5. Include endpoints

None

1516

6. Filter based on genotype QC (FinnGen only)

1490

Control definitions (FinnGen only)

Control exclude AB1_INTESTINAL_INFECTIONS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF5

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 16427 12352 3911
Only index persons 13094 10691 2403
Unadjusted period prevalence (%)
Whole population 0.29 0.35 0.11
Only index persons 0.34 0.39 0.09
Median age at first event (years)
Whole population 35.38 32.81 42.65
Only index persons 32.09 31.32 35.49

-FinnGen-

Key figures

All Female Male
Number of individuals 1490 1195 295
Unadjusted period prevalence (%) 0.41 0.47 0.15
Median age at first event (years) 31.78 29.65 40.41

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

Mortality – FinRegistry

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Association

Association between endpoint AB1_CHOLERA and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have AB1_CHOLERA.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

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Index endpoint: AB1_CHOLERA – Cholera

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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