No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
2670 |
4. Check minimum number of eventsNone |
2670 |
5. Include endpointsNone |
2670 |
6. Filter based on genotype QC (FinnGen only) |
2478 |
Control definitions (FinnGen only)
Control exclude
AB1_SEXUAL_TRANSMISSION
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5
Similar endpoints
↥List of similar endpoints to
Other sexually transmitted chlamydial diseases
based on the number of shared cases.
Similar with more cases:
- Infections with a predominantly sexual mode of transmission
- Certain infectious and parasitic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 27355 | 14515 | 12595 |
| Only index persons | 26769 | 14337 | 12432 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.38 | 0.42 | 0.35 |
| Only index persons | 0.50 | 0.53 | 0.47 |
| Median age at first event (years) | |||
| Whole population | 23.92 | 22.45 | 25.51 |
| Only index persons | 23.86 | 22.45 | 25.50 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2478 | 1627 | 851 |
| Unadjusted period prevalence (%) | 0.57 | 0.64 | 0.43 |
| Median age at first event (years) | 25.10 | 23.35 | 28.46 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint AB1_CHLAMYDIA_OTHER and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_CHLAMYDIA_OTHER | 1.411 [1.1, 1.82] | 0.008 |
| Birth year | 0.995 [0.99, 1.0] | 0.24 |
During the follow-up period (1.1.1998 — 31.12.2019), 79 out of 13290 females with AB1_CHLAMYDIA_OTHER died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_CHLAMYDIA_OTHER | 0.867 [0.73, 1.03] | 0.111 |
| Birth year | 0.985 [0.98, 0.99] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 186 out of 11756 males with AB1_CHLAMYDIA_OTHER died.
Mortality risk
Mortality risk for people of age
years, who have AB1_CHLAMYDIA_OTHER.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.143% | 0.189% |
| 5 | 0.803% | 1.037% |
| 10 | 1.932% | 2.505% |
| 15 | 3.446% | 4.732% |
| 20 | 6.382% | 7.851% |
Relationships between endpoints
↥Index endpoint: AB1_CHLAMYDIA_OTHER – Other sexually transmitted chlamydial diseases
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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