No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
23656 |
4. Check minimum number of eventsNone |
23656 |
5. Include endpointsNone |
23656 |
6. Filter based on genotype QC (FinnGen only) |
22704 |
Control definitions (FinnGen only)
Control exclude
AB1_OTHER_BACTERIAL
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5
Similar endpoints
↥List of similar endpoints to
Bacterial infection, other or unspecified
based on the number of shared cases.
Similar with more cases:
- Other bacterial diseases
- Certain infectious and parasitic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 198853 | 96283 | 101560 |
| Only index persons | 180496 | 88130 | 92366 |
| Unadjusted period prevalence (%) | |||
| Whole population | 2.79 | 2.76 | 2.84 |
| Only index persons | 3.39 | 3.24 | 3.53 |
| Median age at first event (years) | |||
| Whole population | 71.08 | 72.82 | 69.45 |
| Only index persons | 71.10 | 72.78 | 69.49 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 22704 | 10341 | 12363 |
| Unadjusted period prevalence (%) | 5.23 | 4.06 | 6.21 |
| Median age at first event (years) | 68.01 | 65.12 | 70.43 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint AB1_BACTINF_NOS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_BACTINF_NOS | 3.489 [3.06, 3.98] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 31887 out of 73385 females with AB1_BACTINF_NOS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_BACTINF_NOS | 4.179 [3.61, 4.84] | < 0.001 |
| Birth year | 0.979 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 35624 out of 76422 males with AB1_BACTINF_NOS died.
Mortality risk
Mortality risk for people of age
years, who have AB1_BACTINF_NOS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.3% | 0.561% |
| 5 | 1.555% | 3.139% |
| 10 | 3.683% | 8.104% |
| 15 | 6.713% | 14.716% |
| 20 | 11.667% | 22.671% |
Relationships between endpoints
↥Index endpoint: AB1_BACTINF_NOS – Bacterial infection, other or unspecified
GWS hits: 3
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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