Covid-19 suspected case

U22_COVID19_SUSPECTED

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 U072
  • Cause of death: ICD-10 U072

2 out of 7 registries used, show all original rules.

5433

4. Check minimum number of events

None

5433

5. Include endpoints

None

5433

6. Filter based on genotype QC (FinnGen only)

5146

Control definitions (FinnGen only)

Control conditions not U22_COVID19_CONFIRMED

Extra metadata

First used in FinnGen datafreeze DF6

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 50989 30684 19963
Only index persons 42809 26970 15839
Unadjusted period prevalence (%)
Whole population 0.75 0.88 0.56
Only index persons 0.85 0.99 0.60
Median age at first event (years)
Whole population 33.88 35.56 31.28
Only index persons 38.32 38.63 37.78

-FinnGen-

Key figures

All Female Male
Number of individuals 5146 3739 1407
Unadjusted period prevalence (%) 1.26 1.47 0.71
Median age at first event (years) 48.81 45.67 57.15

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Association

Association between endpoint U22_COVID19_SUSPECTED and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have U22_COVID19_SUSPECTED.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: U22_COVID19_SUSPECTED – Covid-19 suspected case

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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