Covid-19 confirmed case

U22_COVID19_CONFIRMED

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 U071
  • Cause of death: ICD-10 U071

2 out of 7 registries used, show all original rules.

8842

4. Check minimum number of events

None

8842

5. Include endpoints

None

8842

6. Filter based on genotype QC (FinnGen only)

8302

Control definitions (FinnGen only)

Control conditions not U22_COVID19_SUSPECTED

Extra metadata

First used in FinnGen datafreeze DF6

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 39717 19767 19395
Only index persons 34107 17397 16710
Unadjusted period prevalence (%)
Whole population 0.55 0.57 0.54
Only index persons 0.64 0.64 0.64
Median age at first event (years)
Whole population 38.47 38.63 38.37
Only index persons 42.30 42.00 42.60

-FinnGen-

Key figures

All Female Male
Number of individuals 8302 4843 3459
Unadjusted period prevalence (%) 1.83 1.90 1.74
Median age at first event (years) 57.86 52.32 65.61

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Association

Association between endpoint U22_COVID19_CONFIRMED and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have U22_COVID19_CONFIRMED.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: U22_COVID19_CONFIRMED – Covid-19 confirmed case

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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